Gene Therapy To Treat Cardiovascular Disease A Survey to Detect The Possibilities Of Prevention And Management With Genetics Using Data Mining

The coronary artery disorder and cardiac arrhythmias are diseases which are the major causes of death in the many countries. Heart diseases can affect people of all ages. Pharmacologic drugs and device treatments have multiple limitations. There exists more need for better-quality clinical outcomes without side effects. Interventional procedures including angioplasty and ablation have improved the prognosis for patients with ischemia and arrhythmias. However, large subgroups of patients are still left with significant morbidity despite of those therapies. This limitation have prompted extensive investigation into new treatment modalities. Sequencing information of the human genome with the development of gene transfer vectors and delivery systems is done by the researchers. There are tools to target specific genes and pathways that play a role in cardiovascular diseases. Early-stages of clinical studies have been demonstrated in the promising signs of efficiency in some trials with very few side effects. The field of myocardial genetic manipulation is vast because of complex and multifaceted disease mechanisms in myocardial genetic gene products. Many different gene products can be targeted to ameliorate clinical phenotypes. There are several delivery vectors used in the clinic.